Abcam, ab142811, BIO-acetoxime, GSK-3alpha/beta inhibitor

Size: 1mg / 10mg
MW 398.22 g/mol, Purity >98%. Potent and selective GSK-3α/β inhibitor (IC 50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling. Inhibits CD8 + T cell differentiation. Shows antiapoptotic effects.
Key facts
CAS number:667463-85-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:398.22 g/mol,
Molecular formula:C18H12BrN3O3,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biological description:Potent and selective GSK-3α/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces Wnt signaling. Inhibits CD8+ T cell differentiation. Shows antiapoptotic effects.,
Isomeric smiles:CC(=O)O\N=C3/C4CCCCC4N/C3=C1/C2CCC(BR)CC2NC1=O,
InChi:InChI=1S/C18H12BrN3O3/c1-9(23)25-22-16-12-4-2-3-5-13(12)20-17(16)15-11-7-6-10(19)8-14(11)21-18(15)24/h2-8,20H,1H3,(H,21,24)/b17-15-,22-16+,
InChiKey:MENDIXKFTXYTHJ-HPBPSMLHSA-N,
IUPAC Name:3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions