Abcam, ab143423, Oligomycin A, ATP synthase inhibitor

Size: 1mg / 5mg
MW 791.1 Da, Purity >97%. Macrolide antibiotic. ATP synthase inhibitor. Blocks the proton channel (Fo subunit) to uncouple oxidative phosphorylation. Shows antitumor activity. Active in vivo .
Key facts
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:791.1 Da,
Molecular formula:C45H74O11,
PubChem:71312254,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 100 mM,
Biochemical name:(4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20Z,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione,
Biological description:Macrolide antibiotic. ATP synthase inhibitor. Blocks the proton channel (Fo subunit) to uncouple oxidative phosphorylation. Shows antitumor activity. Active in vivo.,
Canonical smiles:CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C,
Isomeric smiles:CCC/1CCC2[C@@H](C([C@H](C3(O2)CC[C@H](C(O3)C[C@H](C)O)C)C)OC(=O)/C=C/[C@H]([C@@H]([C@H](C(=O)[C@@H]([C@H]([C@@H](C(=O)[C@@]([C@@H]([C@H](C/C=C/C=C1)C)O)(C)O)C)O)C)C)O)C)C,
InChi:InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+/t25-,26-,27+,28+,29+,30-,31+,32+,33-,34?,35?,36?,38+,40-,41?,42-,44+,45?/m1/s1,
InChiKey:MNULEGDCPYONBU-HXTAVOSMSA-N,
IUPAC Name:(4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20Z,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months