Abcam, ab144269, Heptelidic acid (Koningic acid), GAPDH inhibitor

Size: 250µg / 1mg
MW 280.32 Da, Purity >95%. Potent, selective, irreversible GAPDH inhibitor. Selective, competitive DNA polymerase inhibitor. Antibiotic agent. Potently inhibits ATP generation in the glycolytic pathway. Inhibits DNA polymerases β, λ and terminal deoxynucleotidyl transferase (TdT) in family X. Inhibits caspase- 3 induction (IC 50 = 40 μM). Shows antiapoptotic effects.
Key facts
CAS number:57710-57-3,
Purity:>95%,
Form:SolidSee storage information,
Source:Trichoderma sp.,
Molecular weight:280.32 Da,
Molecular formula:C15H20O5,
PubChem:10945834,
Nature:Native,
Solubility:Soluble in DMSO (10 mg/ml)Soluble in ethanol (1 mg/ml)Soluble in methanol (1 mg/ml)Soluble in water (1 mg/ml),
Biochemical name:Heptelidic acid,
Biological description:Potent, selective, irreversible GAPDH inhibitor. Selective, competitive DNA polymerase inhibitor. Antibiotic agent. Potently inhibits ATP generation in the glycolytic pathway. Inhibits DNA polymerases β, λ and terminal deoxynucleotidyl transferase (TdT) in family X. Inhibits caspase- 3 induction (IC50 = 40 μM). Shows antiapoptotic effects.,
Canonical smiles:CC(C)C1CCC2(CO2)C3C1C=C(COC3=O)C(=O)O,
Isomeric smiles:CC(C)[C@H]1CC[C@@]2(CO2)[C@@H]3[C@@H]1C=C(COC3=O)C(=O)O,
InChi:InChI=1S/C15H20O5/c1-8(2)10-3-4-15(7-20-15)12-11(10)5-9(13(16)17)6-19-14(12)18/h5,8,10-12H,3-4,6-7H2,1-2H3,(H,16,17)/t10-,11-,12-,15-/m1/s1,
InChiKey:JESMSCGUTIEROV-RTWAVKEYSA-N,
IUPAC Name:(5aS,6R,9S,9aS)-1-oxo-6-propan-2-ylspiro[3,5a,6,7,8,9a-hexahydro-2-benzoxepine-9,2'-oxirane]-4-carboxylic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months