Abcam, ab144501, Pyrimidyn-7™, dynamin inhibitor

Size: 5mg
MW 363.59 g/mol, Purity >97%. Novel, potent dual action dynamin inhibitor (IC 50 values are 1.1 and 1.8 µM at dynamin I and II respectively). Only inhibitor to target two distinct domains of dynamin. Competitively inhibits both GTP and phospholipid binding. Reversibly inhibits clathrin mediated endocytosis (CME) and synaptic vesicle endocytosis (SVE) in nerve terminals.
Key facts
CAS number:1440126-94-2,
Purity:>97%,
Form:LiquidSee storage information,
Molecular weight:363.59 g/mol,
Nature:Synthetic,
Biological description:Novel, potent dual action dynamin inhibitor (IC50 values are 1.1 and 1.8 µM at dynamin I and II respectively). Only inhibitor to target two distinct domains of dynamin.Competitively inhibits both GTP and phospholipid binding. Reversibly inhibits clathrin mediated endocytosis (CME) and synaptic vesicle endocytosis (SVE) in nerve terminals.,
Canonical smiles:CN(C)CCNC1NC(C)CC(NCCCCCCCCCCCC)N1,
InChi:InChI=1S/C21H41N5/c1-5-6-7-8-9-10-11-12-13-14-15-22-20-18-19(2)24-21(25-20)23-16-17-26(3)4/h18H,5-17H2,1-4H3,(H2,22,23,24,25),
InChiKey:CKRZZHPNUCLRBE-UHFFFAOYSA-N,
IUPAC Name:N2-[2-(Dimethylamino)ethyl]-N4-dodecyl-6-methyl-2,4-pyrimidinediamine

Product details:
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pyrimidyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions