Abcam, ab144521, BAY 41-2272, Soluble guanylyl cyclase (sGC) activator

Size: 5mg
MW 360.4 Da, Purity >98%. Soluble guanylyl cyclase (sGC) activator. Induces cGMP synthesis independent of NO. Potent platelet aggregation inhibitor (IC 50 = 36 nM). Shows antivasoconstrictive effects (IC 50 = 0.30 μM). Induces phagocytosis. Shows vasodilatory effects in vivo. .
Key facts
CAS number:256376-24-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:360.4 Da,
Molecular formula:C20H17FN6,
PubChem:9798973,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Bay 41-2272,
Biological description:Soluble guanylyl cyclase (sGC) activator. Induces cGMP synthesis independent of NO. Potent platelet aggregation inhibitor (IC50 = 36 nM). Shows antivasoconstrictive effects (IC50 = 0.30 μM). Induces phagocytosis. Shows vasodilatory effects in vivo.,
Canonical smiles:C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F,
InChi:InChI=1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25),
InChiKey:ATOAHNRJAXSBOR-UHFFFAOYSA-N,
IUPAC Name:5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months