Abcam, ab144542, TLCK (Tosyl-L-lysyl-chloromethane hydrochloride), Trypsin inhibitor

Size: 200mg
MW 369.3 Da, Purity >95%. Irreversible inhibitor of trypsin and trypsin-like serine proteases. Blocks LPS- or cytokine-induced NF-κB activation. Inhibits caspase processing; blocks apoptosis. Active in vitro and in vivo .
Key facts
CAS number:4272-74-6,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:369.3 Da,
Molecular formula:C14H22Cl2N2O3S,
PubChem:73093,
Nature:Synthetic,
Solubility:Soluble in methanol (50mg/mL)Soluble in DMSO (5mM)Soluble in water. Stock solutions up to 10mM can be prepared in aqueous buffers with pH 6.0 or lower.,
Biochemical name:N-alpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride,
Biological description:Irreversible inhibitor of trypsin and trypsin-like serine proteases. Blocks LPS- or cytokine-induced NF-κB activation. Inhibits caspase processing; blocks apoptosis. Active in vitro and in vivo.,
Canonical smiles:CC1=CC=C(C=C1)S(=O)(=O)NC(CCCCN)C(=O)CCl.Cl,
Isomeric smiles:CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl.Cl,
InChi:InChI=1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1,
InChiKey:YFCUZWYIPBUQBD-ZOWNYOTGSA-N,
IUPAC Name:N-[(3S)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide;hydrochloride

Product details:
This product has been reported to be very unstable in solutions with a pH above 6, at 25

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months