Abcam, ab144607, Z-Asp-CH2-DCB, caspase inhibitor

Size: 10mg / 50mg
MW 454.3 Da, Purity >98%. Irreversible, cell permeable broad-spectrum caspase inhibitor (IC 50 values are 1.1 and 4.1 μM for caspase-3 and caspase-6 respectively). Inhibits hypoxia-induced apoptosis. Shows anti-ischemic effects in vivo. .
Key facts
CAS number:153088-73-4,
Purity:>98%,
Molecular weight:454.3 Da,
Molecular formula:C20H17Cl2NO7,
PubChem:9911778,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:Z-Asp-CH2-DCB,
Biological description:Irreversible, cell permeable broad-spectrum caspase inhibitor (IC50 values are 1.1 and 4.1 μM for caspase-3 and caspase-6 respectively). Inhibits hypoxia-induced apoptosis. Shows anti-ischemic effects in vivo.,
Canonical smiles:C1=CC=C(C=C1)COC(=O)NC(CC(=O)O)C(=O)COC(=O)C2=C(C=CC=C2Cl)Cl,
Isomeric smiles:C1=CC=C(C=C1)COC(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)C2=C(C=CC=C2Cl)Cl,
InChi:InChI=1S/C20H17Cl2NO7/c21-13-7-4-8-14(22)18(13)19(27)29-11-16(24)15(9-17(25)26)23-20(28)30-10-12-5-2-1-3-6-12/h1-8,15H,9-11H2,(H,23,28)(H,25,26)/t15-/m0/s1,
InChiKey:FKJMFCOMZYPWCO-HNNXBMFYSA-N,
IUPAC Name:(3S)-5-(2,6-dichlorobenzoyl)oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months