Abcam, ab144650, Pitstop® 2-100, clathrin terminal domain inhibitor

Size: 5mg
MW 463.35 g/mol, Purity >99%. Novel clathrin terminal domain inhibitor (IC 50 = 7.5 μM). Specifically inhibits the internalisation of major histocompatibility complex 1 (MHC1). Related products Pitstop ® 2 (ab120687), Pitstop ® 1 (ab120686) and Pitstop ® 1-25 (ab144651).
Key facts
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:463.35 g/mol,
Nature:Synthetic,
Solubility:Soluble in DMSO,
Biological description:Novel clathrin terminal domain inhibitor (IC50 = 7.5 μM). Specifically inhibits the internalisation of major histocompatibility complex 1 (MHC1). Related products Pitstop® 2 (ab120687), Pitstop® 1 (ab120686) and Pitstop® 1-25 (ab144651).,
Isomeric smiles:O=C4N=C(NS(=O)(=O)C2CCCC1CCCCC12)S\C4=C/C3CC(CL)CC(CL)C3,
InChi:InChI=1S/C20H12Cl2N2O3S2/c21-14-8-12(9-15(22)11-14)10-17-19(25)23-20(28-17)24-29(26,27)18-7-3-5-13-4-1-2-6-16(13)18/h1-11H,(H,23,24,25)/b17-10-,
InChiKey:LSNZIDXWMYTGMW-YVLHZVERSA-N,
IUPAC Name:(Z)-N-[5-(3,5-Dichlorobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl]naphthalene-1-sulfonamide

Product details:
Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months