Abcam, ab144822, BMS 345541, IKK-2 and IKK-1 inhibitor

Size: 5mg / 10mg / 50mg
MW 255.32 Da, Purity >98%. Highly selective cell permeable IKK-2 and IKK-1 inhibitor (IC 50 values are 0.3 and 4 μM for IKK-2 and IKK-1 respectively). Blocks NF-κB-dependent transcription. Shows anti-inflammatory and radiosensitizing effects in vivo. Orally active.
Key facts
CAS number:445430-58-0,
Purity:>98%,
Molecular weight:255.32 Da,
Molecular formula:C14H17N5,
PubChem:9813758,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biochemical name:BMS-345541 free base,
Biological description:Highly selective cell permeable IKK-2 and IKK-1 inhibitor (IC50 values are 0.3 and 4 μM for IKK-2 and IKK-1 respectively). Blocks NF-κB-dependent transcription. Shows anti-inflammatory and radiosensitizing effects in vivo. Orally active.,
Canonical smiles:CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN,
InChi:InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18),
InChiKey:PSPFQEBFYXJZEV-UHFFFAOYSA-N,
IUPAC Name:N'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions