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BRAND / VENDOR: Abcam

Abcam, ab144849, OM173-alphaA, DNMT3B and FTase inhibitor

CATALOG NUMBER: ab144849
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Product Description

Size: 1mg / 5mg
MW 316.3 Da, Purity >95%. Potent, selective DNA (cytosine-5)-methyltransferase 3B (DNMT3B) inhibitor (IC 50 = 500nM). Farnesyltransferase (FTase) inhibitor (IC 50 = 3.2μM). Antibiotic and antimycoplasmal agent. Nanaomycin A methyl ester.
Key facts
CAS number:58286-56-9,
Purity:>95%,
Form:SolidSee storage information,
Source:Streptomyces sp.,
Molecular weight:316.3 Da,
Molecular formula:C17H16O6,
PubChem:12803368,
Nature:Native,
Solubility:Soluble in DMSOSoluble in ethanol,
Biochemical name:OM173-alphaA,
Biological description:Potent, selective DNA (cytosine-5)-methyltransferase 3B (DNMT3B) inhibitor (IC50 = 500nM). Farnesyltransferase (FTase) inhibitor (IC50 = 3.2μM). Antibiotic and antimycoplasmal agent. Nanaomycin A methyl ester.,
Canonical smiles:CC1C2=C(CC(O1)CC(=O)OC)C(=O)C3=C(C2=O)C(=CC=C3)O,
Isomeric smiles:C[C@H]1C2=C(C[C@@H](O1)CC(=O)OC)C(=O)C3=C(C2=O)C(=CC=C3)O,
InChi:InChI=1S/C17H16O6/c1-8-14-11(6-9(23-8)7-13(19)22-2)16(20)10-4-3-5-12(18)15(10)17(14)21/h3-5,8-9,18H,6-7H2,1-2H3/t8-,9+/m0/s1,
InChiKey:FMEUWIKCSICJBO-DTWKUNHWSA-N,
IUPAC Name:methyl 2-[(1S,3R)-9-hydroxy-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-3-yl]acetate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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