Abcam, ab145066, ISCK03, SCF/c-Kit inhibitor

Size: 5mg / 25mg
MW 355.5 Da, Purity >99%. Cell-permeable, selective SCF/c-Kit inhibitor (IC 50 < 2.5 μM). Blocks SCF-induced c-kit and Erk phosphorylation without affecting HGF-induced Erk phosphorylation. Shows antiangiogenic effects. Abolishes melanin production in vivo. .
Key facts
CAS number:945526-43-2,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:355.5 Da,
Molecular formula:C19H21N3O2S,
PubChem:3792751,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,
Biochemical name:tert-Butylphenyl imidazolylphenyl sulfonamide,
Biological description:Cell-permeable, selective SCF/c-Kit inhibitor (IC50 < 2.5 μM). Blocks SCF-induced c-kit and Erk phosphorylation without affecting HGF-induced Erk phosphorylation. Shows antiangiogenic effects. Abolishes melanin production in vivo.,
Canonical smiles:CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N3C=CN=C3,
InChi:InChI=1S/C19H21N3O2S/c1-19(2,3)15-4-10-18(11-5-15)25(23,24)21-16-6-8-17(9-7-16)22-13-12-20-14-22/h4-14,21H,1-3H3,
InChiKey:XQABBHBFHWHMKF-UHFFFAOYSA-N,
IUPAC Name:4-tert-butyl-N-(4-imidazol-1-ylphenyl)benzenesulfonamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months