Abcam, ab145171, beta-Elemene, Anticancer agent

Size: 25mg / 100mg / 500mg
MW 204.35 Da. Anticancer agent. Induces G 2 M cell cycle arrest and apoptosis. Induces caspase-3, -7 and -9 activities. Decreases Bcl-2 expression. Induces mitochondrial release of cytochrome c. Inhibits microtubule polymerization. Downregulates uPA, uPAR, MMP-2, and MMP-9 expression. Shows antiproliferative effects. Shows antitumor effects in vivo. .
Key facts
CAS number:515-13-9,
Source:Curcuma aromatica,
Molecular weight:204.35 Da,
Molecular formula:C15H24,
PubChem:10583,
Nature:Native,
Biochemical name:Cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1R,2R,4S)-rel-,
Biological description:Anticancer agent. Induces G2M cell cycle arrest and apoptosis. Induces caspase-3, -7 and -9 activities. Decreases Bcl-2 expression. Induces mitochondrial release of cytochrome c. Inhibits microtubule polymerization. Downregulates uPA, uPAR, MMP-2, and MMP-9 expression. Shows antiproliferative effects. Shows antitumor effects in vivo.,
Canonical smiles:CC(=C)C1CCC(C(C1)C(=C)C)(C)C=C,
InChi:InChI=1S/C15H24/c1-7-15(6)9-8-13(11(2)3)10-14(15)12(4)5/h7,13-14H,1-2,4,8-10H2,3,5-6H3,
InChiKey:OPFTUNCRGUEPRZ-UHFFFAOYSA-N,
IUPAC Name:1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane

Product details:
β-Elemene exists as a liquid in its pure form at room temperature. There is no concentration because product itself is pure β-Elemene. Its appearance is clear and colorless liquid.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months