Abcam, ab145189, IC 261, CK1delta and CK1epsilon inhibitor

Size: 5mg / 25mg
MW 311.3 Da, Purity >99%. Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor. Induces cell cycle arrest and apoptosis. Selectively inhibits tumor cells growth. Shows antitumor effects in vivo. .
Key facts
CAS number:186611-52-9,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:311.3 Da,
Molecular formula:C18H17NO4,
PubChem:5353678,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:(3Z)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one,
Biological description:Selective CK1δ and CK1ε inhibitor. Potent microtubulin polymerization inhibitor. Induces cell cycle arrest and apoptosis. Selectively inhibits tumor cells growth. Shows antitumor effects in vivo.,
Canonical smiles:COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC,
Isomeric smiles:COC1=CC(=C(C(=C1)OC)/C=C\2/C3=CC=CC=C3NC2=O)OC,
InChi:InChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10-,
InChiKey:JBJYTZXCZDNOJW-RAXLEYEMSA-N,
IUPAC Name:(3Z)-3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions