Abcam, ab145194, AS601245, JNK inhibitor

Size: 1mg / 5mg / 25mg
MW 372.4 Da, Purity >95%. Potent, selective, ATP competitive JNK inhibitor (IC 50 values are 150, 220 and 70 nM for hJNK1,2 and 3 respectively). Reduces cell adhesion and migration in cancer cells. Shows neuroprotective, anti-ischemic effects in vivo . Blood-brain barrier and cell-permeable.
Key facts
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:372.4 Da,
Molecular formula:C20H16N6S,
PubChem:11422035,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biochemical name:JNK Inhibitor V,
Biological description:Potent, selective, ATP competitive JNK inhibitor (IC50 values are 150, 220 and 70 nM for hJNK1,2 and 3 respectively). Reduces cell adhesion and migration in cancer cells. Shows neuroprotective, anti-ischemic effects in vivo. Blood-brain barrier and cell-permeable.,
Canonical smiles:C1=CC=C2C(=C1)NC(=C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4)S2,
Isomeric smiles:C1=CC=C2C(=C1)N/C(=C(/C#N)\C3=NC(=NC=C3)NCCC4=CN=CC=C4)/S2,
InChi:InChI=1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,25H,7,10H2,(H,23,24,26)/b19-15+,
InChiKey:AVLYNJZZQYEFEA-XDJHFCHBSA-N,
IUPAC Name:(2Z)-2-(3H-1,3-benzothiazol-2-ylidene)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months