Abcam, ab145223, IDE 2, endoderm formation inducer

Size: 1mg
MW 240.3 Da, Purity >98%. Cell-permeable definitive endoderm formation inducer (EC 50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. .
Key facts
CAS number:1136466-93-7,
Purity:>98%,
Molecular weight:240.3 Da,
Molecular formula:C12H20N2O3,
PubChem:23836158,
Nature:Synthetic,
Solubility:Soluble in water to 20 mMSoluble in ethanol to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:7-(2-Cyclopentylidenehydrazinyl)-7-oxoheptanoic acid,
Biological description:Cell-permeable definitive endoderm formation inducer (EC50 = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo.,
Canonical smiles:C1CCC(=NNC(=O)CCCCCC(=O)O)C1,
InChi:InChI=1S/C12H20N2O3/c15-11(8-2-1-3-9-12(16)17)14-13-10-6-4-5-7-10/h1-9H2,(H,14,15)(H,16,17),
InChiKey:CVYPYYPTFNVREL-UHFFFAOYSA-N,
IUPAC Name:7-(2-cyclopentylidenehydrazinyl)-7-oxoheptanoic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months