Abcam, ab145232, Luzindole (N-0774), melatonin receptor antagonist

Size: 25mg
MW 292.4 Da, Purity >96%. Competitive melatonin receptor antagonist (IC 50 = 1 μM). Shows selectivity towards melatonin 1B (K i values are 45 and 603 nM for MEL-1B and MEL-1A respectively). Inhibits melatonin-induced pigment aggregation (IC 50 = 2.1 μM) and shows neuroprotective effects in vivo. .
Key facts
CAS number:117946-91-5,
Purity:>96%,
Molecular weight:292.4 Da,
Molecular formula:C19H20N2O,
PubChem:122162,
Nature:Synthetic,
Solubility:Soluble in ethanol to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:Luzindole,
Biological description:Competitive melatonin receptor antagonist (IC50 = 1 μM). Shows selectivity towards melatonin 1B (Ki values are 45 and 603 nM for MEL-1B and MEL-1A respectively). Inhibits melatonin-induced pigment aggregation (IC50 = 2.1 μM) and shows neuroprotective effects in vivo.,
Canonical smiles:CC(=O)NCCC1=C(NC2=CC=CC=C21)CC3=CC=CC=C3,
InChi:InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22),
InChiKey:WVVXBPKOIZGVNS-UHFFFAOYSA-N,
IUPAC Name:N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months