Abcam, ab145869, Reversan, MRP1 and P-glycoprotein inhibitor

Size: 10mg / 50mg
MW 441.53 g/mol, Purity >99%. Selective MRP1 and P-glycoprotein inhibitor. Chemosensitizing agent. Increases the sensitivity of MRP1-overexpressing tumor cells to doxorubicin (ab120629), vincristine (ab120226) and etoposide (ab120227). Shows chemosensitizing, antitumor effects in vivo. .
Key facts
CAS number:313397-13-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:441.53 g/mol,
Molecular formula:C26H27N5O2,
Nature:Synthetic,
Solubility:Soluble in ethanol to 5 mMSoluble i in DMSO to 25 mM,
Biological description:Selective MRP1 and P-glycoprotein inhibitor. Chemosensitizing agent. Increases the sensitivity of MRP1-overexpressing tumor cells to doxorubicin (ab120629), vincristine (ab120226) and etoposide (ab120227). Shows chemosensitizing, antitumor effects in vivo.,
Canonical smiles:C1COCCN1CCCNC(=O)C2=C3N=C(C=C(N3N=C2)C4=CC=CC=C4)C5=CC=CC=C5,
InChi:InChI=1S/C26H27N5O2/c32-26(27-12-7-13-30-14-16-33-17-15-30)22-19-28-31-24(21-10-5-2-6-11-21)18-23(29-25(22)31)20-8-3-1-4-9-20/h1-6,8-11,18-19H,7,12-17H2,(H,27,32),
InChiKey:JTRXWCLQFAZHGP-UHFFFAOYSA-N,
IUPAC Name:N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months