Abcam, ab146155, Importazole, nuclear transport receptor importin-beta inhibitor

Size: 5mg / 25mg
MW 318.42 g/mol, Purity >99%. Selective nuclear transport receptor importin-β inhibitor (IC 50 = 25 μM). Blocks SINC localization at the nuclear envelope. Impairs release of importin-β cargo and induces defects in defects in spindle assembly during mitosis.
Key facts
CAS number:662163-81-7,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:318.42 g/mol,
Molecular formula:C20H22N4,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,
Biological description:Selective nuclear transport receptor importin-β inhibitor (IC50 = 25 μM). Blocks SINC localization at the nuclear envelope. Impairs release of importin-β cargo and induces defects in defects in spindle assembly during mitosis.,
Canonical smiles:CC(NC1NC(NC2CCCCC12)N3CCCC3)C4CCCCC4,
InChi:InChI=1S/C20H22N4/c1-15(16-9-3-2-4-10-16)21-19-17-11-5-6-12-18(17)22-20(23-19)24-13-7-8-14-24/h2-6,9-12,15H,7-8,13-14H2,1H3,(H,21,22,23),
InChiKey:HKGJEZIGDHFJFL-UHFFFAOYSA-N,
IUPAC Name:N-(1-Phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months