Abcam, ab146161, BRD-7389, p90 ribosomal S6 kinase RSK inhibitor

Size: 5mg / 25mg
MW 366.4 Da. p90 ribosomal S6 kinase RSK inhibitor (IC 50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.
Key facts
Form:SolidSee storage information,
Molecular weight:366.4 Da,
Molecular formula:C24H18N2O2,
PubChem:24870634,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:16-(2-Phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13-heptaene-8,15-dione,
Biological description:p90 ribosomal S6 kinase RSK inhibitor (IC50 values are 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in pancreatic α-cells. Shows reprogramming effects in terminally differentiated cells.,
Canonical smiles:C1=CC=C(C=C1)CCNC2=C3C4C(=NC2=O)C=CC=C4C(=O)C5=CC=CC=C53,
InChi:InChI=1S/C24H18N2O2/c27-23-17-10-5-4-9-16(17)21-20-18(23)11-6-12-19(20)26-24(28)22(21)25-14-13-15-7-2-1-3-8-15/h1-12,20,25H,13-14H2,
InChiKey:QVEVXIXBUORVGE-UHFFFAOYSA-N,
IUPAC Name:16-(2-phenylethylamino)-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9,11,13-heptaene-8,15-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months