Abcam, ab146176, STF-083010, IRE1alpha endonuclease inhibitor

Size: 5mg / 25mg
MW 317.4 Da. Selective IRE1α endonuclease inhibitor. Dose dependently inhibits XBP-1 splicing. Shows cancer cell selective cytotoxic and cytostatic antiproliferative effects. Shows antitumor effects in vivo. .
Key facts
CAS number:307543-71-1,
Form:SolidSee storage information,
Molecular weight:317.4 Da,
Molecular formula:C15H11NO3S2,
PubChem:6537512,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:CID 6537512,
Biological description:Selective IRE1α endonuclease inhibitor. Dose dependently inhibits XBP-1 splicing. Shows cancer cell selective cytotoxic and cytostatic antiproliferative effects. Shows antitumor effects in vivo.,
Canonical smiles:C1=CC=C2C(=C1)C=CC(=O)C2=CNS(=O)(=O)C3=CC=CS3,
Isomeric smiles:C1=CC=C\2C(=C1)C=CC(=O)/C2=C\NS(=O)(=O)C3=CC=CS3,
InChi:InChI=1S/C15H11NO3S2/c17-14-8-7-11-4-1-2-5-12(11)13(14)10-16-21(18,19)15-6-3-9-20-15/h1-10,16H/b13-10-,
InChiKey:AUXKGDNZANYAPX-RAXLEYEMSA-N,
IUPAC Name:N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]thiophene-2-sulfonamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months