Abcam, ab146189, DMAPT, NF-kappaB inhibitor

Size: 5mg / 25mg
MW 293.41 g/mol. NF-κB inhibitor. Reduces NF-κB DNA binding. Shows antiproliferative effects (IC 50 = 5-10 μM). Parthenolide (ab120849) analog. Epigenetic modulator, functions NFκB-dependently and independently. Generates ROS and shows antitumor effects in vivo. Orally active.
Key facts
CAS number:870677-05-7,
Form:SolidSee storage information,
Molecular weight:293.41 g/mol,
Molecular formula:C17H27NO3,
Nature:Synthetic,
Biological description:NF-κB inhibitor. Reduces NF-κB DNA binding. Shows antiproliferative effects (IC50 = 5-10 μM). Parthenolide (ab120849) analog. Epigenetic modulator, functions NFκB-dependently and independently. Generates ROS and shows antitumor effects in vivo. Orally active.,
IUPAC Name:(1aR,4E,7aS,8R,10aS,10bS)-8-[(Dimethylamino)methyl]-2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months