Abcam, ab157107, Anti-CD44 antibody

Size: 100µL
Anti-CD44 antibody (ab157107) is a rabbit polyclonal antibody detecting CD44 in Western Blot, IP, IHC-P . Suitable for Human, Mouse, Rat . - Over 180 publications
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:WB, IP, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human CD44 aa 650 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.P16070

Product details:
Product Specifications
Anti-CD44 antibody (ab157107) is a rabbit polyclonal antibody and is validated for use in IHC-P, IP, WB in human, mouse, rat samples.
Anti-CD44 antibody (ab157107) specifically detects CD44 (UniProt ID: P16070; Molecular weight: 79kDa) and is sold in 100 µL selling sizes.
Quality and Validation
Abcam's high quality validation processes ensure Anti-CD44 antibody (ab157107) has high sensitivity and specificity.
Anti-CD44 antibody (ab157107) has been cited over 188 times in peer reviewed journals and is trusted by the scientific community.
Anti-CD44 antibody (ab157107) has 31 independent reviews from customers.
Target Information
CD44 is a cell-surface glycoprotein involved in various physiological functions such as cell proliferation, adhesion, migration, and lymphocyte activation. It plays a significant role in the pathology of diseases like cancer, arthritis, and infections by interacting with its principal ligand, hyaluronic acid. CD44 plays a significant role in autoimmune diseases by mediating inflammatory responses and immune cell interactions. It is involved in the activation and migration of lymphocytes, which are crucial in the development of autoimmune conditions. For instance, targeting CD44 with monoclonal antibodies has shown anti-inflammatory effects in murine models of autoimmune diseases like arthritis and experimental autoimmune encephalomyelitis (EAE)

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab157107 was affinity purified using an epitope specific to CD44 immobilized on solid support., Storage buffer-pH: 7 - 8Preservative: 0.09% Sodium azideConstituents: 99% Tris citrate/phosphate, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C