Abcam, ab161678, Recombinant Human SEC14 like protein 2

Size: 10µg
Recombinant Human SEC14 like protein 2 is a Human Fragment protein, in the 101 to 199 aa range, expressed in Wheat germ, suitable for ELISA, WB.
Key facts
Expression system:Wheat germ,
Tags:GST tag N-Terminus,
Applications:ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Biologically active:No,
Accession:O76054,
Animal free:No,
Carrier free:No,
Species:Human,
Storage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione

Properties and Storage Information:
Shipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
SEC14 like protein 2 also known as SEC14L2 participates in lipid binding and transport. This protein weighs about 45 kDa and plays a role in lipid metabolism. Expression of SEC14L2 can be found in multiple tissues including the liver and spleen. By interacting with lipids SEC14L2 modulates cellular lipid environments and influences various cellular processes.
Biological function summary
This protein interacts with other lipid transfer proteins and is involved in lipid homeostasis. SEC14L2 does not act alone; it often forms part of lipid protein complexes that facilitate the transport of lipids across biological membranes. These complexes enable SEC14L2 to contribute to the maintenance of membrane integrity and facilitate signal transduction pathways.
Pathways
This protein participates in lipid metabolism and phosphatidylinositide signaling pathways. In the regulation of these pathways SEC14L2 interacts with proteins like phosphatidylinositol 3-kinase (PI3K). Through these interactions SEC14L2 supports critical cellular functions such as membrane trafficking and signaling that depend on lipid dynamics.
Research links SEC14L2 to liver diseases like hepatitis C and its expression influences antiviral defense mechanisms. Additionally SEC14L2 associates with proteins involved in cholesterol metabolism contributing to atherosclerosis development. By understanding SEC14L2's role researchers aim to find therapeutic targets for these conditions.