Abcam, ab163926, Recombinant Human SPATS2 protein

Size: 10µg
Recombinant Human SPATS2 protein is a Human Full Length protein, in the 1 to 545 aa range, expressed in Wheat germ, suitable for ELISA, WB.
Key facts
Expression system:Wheat germ,
Tags:GST tag N-Terminus,
Applications:ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Biologically active:No,
Accession:Q86XZ4,
Animal free:No,
Carrier free:No,
Species:Human,
Storage buffer:pH: 8Constituents: 0.79% Tris HCl, 0.31% Glutathione

Properties and Storage Information:
Shipped at conditions-Dry Ice, Appropriate short-term storage conditions--80°C, Appropriate long-term storage conditions--80°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
SPATS2 also known as spermatogenesis-associated serine-rich protein 2 is an interesting target in the study of protein functions. It has a mass of around 43 kDa. This protein is expressed in several tissues with a higher presence in testis which suggests a potential role in reproductive processes. SPATS2 localizes mostly to the cytoplasm of cells where it takes part in direct protein interactions and other cellular activities.
Biological function summary
Proteins similar to SPATS2 are linked to regulatory roles during cell processes. SPATS2 does not function in isolation but partners with other proteins to manage cellular growth and differentiation. It does not form part of a larger complex but may influence other protein activities through signaling pathways. Ongoing research explores how SPATS2 impacts regulation mechanisms especially considering its expression patterns and potential links to cellular proliferation.
Pathways
Proteins like SPATS2 connect and interact within signal transduction pathways including the PI3K/AKT pathway. This pathway plays an important role in managing cell survival and growth. SPATS2 may collaborate with proteins such as AKT1 and PDK1 to influence these pathways. These signal cascades often dictate cell behavior making SPATS2 an important player in understanding cell signaling networks and their consequences on cellular functions.
SPATS2 involvement has been suggested in specific types of cancer due to its expression patterns. Research suggests a connection between SPATS2 and prostate cancer; its regulation might influence tumor growth. This relationship associates SPATS2 with proteins like PTEN a known tumor suppressor involved in cancer progression. Understanding these interactions could provide insights into therapeutic opportunities that target or modulate SPATS2 within affected patients.