Abcam, ab166607, Anti-FAM96B antibody [EPR10178]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal FAM96B antibody. Suitable for IP, WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 4 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR10178,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:Flow Cyt (Intra), WB, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
FAM96B also known as Family with sequence similarity 96 member B is a small protein with a mass of approximately 23 kilodaltons. This protein is expressed in various human tissues with notable expression in the heart and skeletal muscle. FAM96B may play significant roles in cellular function due to its involvement in protein-protein interactions. Researchers study FAM96B to understand its role in cellular transport processes and regulation.
Biological function summary
FAM96B participates in the assembly and stabilization of cytosolic iron-sulfur cluster assembly machinery. It acts as a binding partner in the CIA complex (cytosolic iron-sulfur assembly). This complex is important for the maturation of cytosolic and nuclear iron-sulfur proteins which influences multiple cellular processes. The protein's interactions within the complex allow it to contribute to proper cellular iron homeostasis and genome stability.
Pathways
Several important cellular functions relate to the presence of FAM96B. The cytosolic iron-sulfur cluster assembly pathway is significant serving a role in iron homeostasis and DNA repair. FAM96B interacts with proteins such as CIA2B and MMS19 which are components of the CIA complex. These interactions are well-documented and they play a role in the broader network of cellular maintenance and repair pathways.
FAM96B has been studied for its connection to cancer and neurodegenerative diseases. Abnormal expression or function of FAM96B may impact iron metabolism which is linked to these conditions. In cancer disrupted iron-sulfur proteins can affect cellular proliferation and apoptosis. FAM96B works closely with proteins like CIA2B and MMS19 which when dysregulated may contribute to disease progression. Researchers continue exploring these links to understand FAM96B's potential as a therapeutic target.