Abcam, ab168370, Anti-GAS-7 antibody [EPR11129(B)]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal GAS-7 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human, Mouse, Rat samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR11129(B),
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Growth Arrest-Specific 7 often known as GAS7 is a protein with a molecular weight of approximately 48 kDa. GAS7 is known for its expression in neural tissues particularly in the brain where it plays an important role in cellular processes. This protein participates in the growth arrest of cells specifically in neurons indicating its importance in neurological functions.
Biological function summary
GAS7 contributes to the regulation of neuronal development and morphology. It is a part of various cellular complexes that guide the proper formation and differentiation of neurons. Studies show it helps in the development of the nerve cell cytoskeleton which is critical for maintaining neuronal architecture and function.
Pathways
The involvement of GAS7 includes those related to cytoskeletal organization and neuronal differentiation. Two significant pathways include the MAPK signaling pathway and the PI3K-Akt signaling pathway. GAS7 interacts with other proteins such as actin and filamin which are essential components in these pathways to regulate cell shape and motility.
GAS7 is linked to certain neurological conditions like neurodegenerative disorders and developmental issues. Abnormalities in GAS7 expression or function may have connections to disorders like Alzheimer's disease where cytoskeletal anomalies are common. Additionally its interaction with the protein tau which is implicated in Alzheimer's highlights its potential role in the manifestation of such diseases.