Abcam, ab171736, Anti-DHRSX antibody [EPR7753(2)]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal DHRSX antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR7753(2),
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:Flow Cyt (Intra), WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
DHRSX (Dehydrogenase/Reductase (SDR Family) Member X) is a protein of interest in various biological studies. It is known for its role in oxidoreductase activity and commonly does not have other alternate names. The protein mass is approximately 37 kDa. DHRSX expresses in multiple tissues with notable expression in the brain and liver suggesting a diverse role across different systems.
Biological function summary
The protein DHRSX affects cellular processes by participating in metabolism. It does not seem to be a part of a larger protein complex indicating its function may rely more on individual activity. Its capability to act in reduction-oxidation reactions helps cells manage oxidative stress and maintain metabolic balance. The effects of DHRSX have implications in normal cellular function and development.
Pathways
DHRSX is important in the metabolic and detoxification pathways. It engages with the NADP/NADPH cofactor system influencing the oxidative status of cells and supporting cellular defense against reactive oxygen species. Additionally the interaction with proteins like ADH1 (Alcohol Dehydrogenase 1) further integrates DHRSX into enzymatic pathways critical for metabolizing alcohols and aldehydes.
DHRSX has potential links to metabolic syndromes and liver disease. Research has found that irregular DHRSX expression correlates with metabolic disorders like obesity possibly through disruption in glucose and lipid metabolism. The protein's activity appears connected to other metabolic proteins such as PPARα (Peroxisome Proliferator-Activated Receptor Alpha) shedding light on how disturbances in DHRSX can contribute to broader metabolic issues.