Abcam, ab172622, Anti-LMTK2 antibody [EPR7836(2)]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal LMTK2 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR7836(2),
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The LMTK2 protein also known as Lemur Tyrosine Kinase 2 is a serine/threonine kinase with an approximated mass of 150 kDa. It plays an important role in protein phosphorylation influencing various cellular processes. LMTK2 is expressed in multiple tissues notably in the brain and testis. Its kinase activity impacts neurodevelopment and spermatogenesis reflecting its significant presence in these areas.
Biological function summary
LMTK2 influences neuron maintenance and signaling. It is not known to be part of any large protein complex but interacts closely with important cellular proteins. LMTK2 has a regulatory effect on axonal outgrowth and synaptic vesicle transport which are essential for neuron function. Moreover it interacts with other kinases and phosphatases impacting cellular signal transduction pathways.
Pathways
LMTK2 has important roles in the Wnt and MAPK signaling pathways. Within the Wnt pathway LMTK2 modulates cellular growth and differentiation by interacting with proteins like beta-catenin. In the MAPK pathway its influence on kinases helps control cell proliferation and stress responses. The interactions of LMTK2 with these signaling pathways highlight its influence on cell fate decisions and adaptive responses.
LMTK2 associates with neurodegenerative diseases and cancer. Its dysfunction has been linked to Alzheimer's disease where aberrant signaling affects neuronal health. LMTK2 potentially interacts with tau protein impacting tau pathology. In cancer altered LMTK2 expression associates with disrupted cellular growth signaling suggesting a role in tumor progression. Understanding these connections offers insights for therapeutic innovations.