Abcam, ab17293, Anti-Ovalbumin antibody [6C8]

Size: 100µL
Anti-Ovalbumin antibody [6C8] (ab17293) is a mouse monoclonal antibody detecting Ovalbumin in Western Blot, ELISA . Suitable for Chicken . - Over 10 publications - Trusted since 2005
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:6C8,
Isotype:IgG1,
Light chain type:kappa,
Carrier free:No,
Reacts with:Chicken,
Applications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Native Full Length Protein corresponding to Chicken SERPINB14.P01012,
Specificity:The antibody reacts strongly with Ovalbumin (OA) in denatured and modified forms (native OA surface-adsorbed, heat-denatured or reduced).Strong reaction is seen in ELISA, with OA directly coated onto the microtiterwell.In dotblotting it reacts with both native and denatured OA adsorbed onto nitrocellulose.In Western blotting after SDS-PAGE, the antibody reacts with OA in reduced as well as unreduced forms.

Product details:
What is this antibody validated in?
Anti-Ovalbumin antibody [6C8] (ab17293) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), ELISA in Chicken samples.
Trusted by the scientific community
Anti-Ovalbumin [6C8] (ab17293) was first used in a scientific publication in 2005 and has been cited over 10 times in peer-reviewed journals.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Purification notes-Immunized i.p. with immunogen adsorbed onto Al(OH)3., Storage buffer-pH: 7.4Preservative: 0.097% Sodium azideConstituents: PBS, 2.9% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Ovalbumin also known as egg albumin is a significant protein found in egg white representing about 54% of the protein content in this part of the egg. It has a molecular weight of approximately 45 kDa. This protein is synthesized in the oviduct of birds and deposited in the egg white where it fulfills several roles. Ovalbumin is a glycoprotein meaning it has carbohydrate groups attached to the polypeptide chain. Researchers commonly use it as a model antigen in immunology studies and as a standard in protein markers because of its known properties.
Biological function summary
Ovalbumin functions as a storage protein in eggs providing essential amino acids for the developing embryo. This protein also plays a role in binding metal ions and vitamins acting as a nutrient reservoir. It is not part of a complex existing as a single polypeptide chain. Ovalbumin contributes to the regulation and transport of metabolic compounds due to its ability to bind ions. These properties make it useful in various biological studies and industrial applications.
Pathways
Four significant pathways involve the role of ovalbumin in living organisms. These include the regulation of protein adsorption and the nutrient reservoir activity pathway. Ovalbumin's ability to serve as a nutrient source directly relates to these pathways ensuring proper nourishment during embryo development. It operates independently of other proteins in these pathways emphasizing its role in providing and regulating nutrients without the aid of additional complexes.
Ovalbumin has connections to some allergic responses particularly in individuals with egg allergies. It acts as an allergen capable of provoking immune reactions. Ovalbumin lacks a direct connection to specific diseases beyond allergies. However understanding its interaction with immune system proteins like immunoglobulin E (IgE) is important as this is the primary mediator in allergic responses. This link makes ovalbumin important for research into allergy mechanisms and the development of hypoallergenic variants.