Abcam, ab180121, Anti-ZNF24 antibody [EPR13975]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal ZNF24 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13975,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ZNF24 also known as zinc finger protein 191 is a transcription factor with a molecular weight of approximately 55 kDa. It functions by binding to specific DNA sequences through its zinc finger domains thereby influencing the transcription of genes. The expression of ZNF24 occurs in various tissues including the liver lung and brain suggesting its role in multiple cellular processes. This protein plays a significant role in gene regulation due to its ability to bind DNA and modulate the expression of specific genes.
Biological function summary
Zinc finger protein 191 regulates cell proliferation differentiation and development. It does not typically form part of a larger protein complex acting mostly as a solitary transcription factor. By influencing the expression of genes involved in cell cycle progression and differentiation ZNF24 contributes to maintaining cellular homeostasis. Alterations in its expression can affect these biological processes leading to various cellular dysfunctions and abnormalities.
Pathways
Zinc finger protein 191 plays a role in the Wnt signaling and cell cycle pathways. In the Wnt signaling pathway ZNF24 modulates the transcription of target genes that are essential for cell proliferation and differentiation. In the cell cycle pathway it interacts directly with proteins such as cyclins and cyclin-dependent kinases which are important for the control of cell cycle transitions. This involvement in key signaling pathways highlights its importance in regulating cellular growth and division.
Zinc finger protein 191 has been linked to cancer and neurodegenerative diseases. In cancer ZNF24 dysregulation can lead to uncontrolled cell proliferation as it interacts with proteins like β-catenin within the Wnt signaling pathway. In neurodegenerative diseases the altered expression of ZNF24 affects neuronal cell function as it potentially interacts with amyloid precursor proteins disrupting normal neuronal processes. These connections indicate the potential implications of ZNF24 in both oncogenesis and neurodegenerative conditions.