Abcam, ab181031, Anti-C8orf30A antibody [EPR13203-28]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal C8orf30A antibody. Suitable for IHC-P, IP, WB, ICC/IF and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR13203-28,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WB, IP, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The C8orf30A protein also called Chromosome 8 open reading frame 30A has a molecular mass of about 12 kDa. This protein's function involves cellular processes related to energy metabolism and plays an unclear yet significant mechanical role in the cells. Expression of C8orf30A occurs in tissues that display high metabolic activity such as liver and muscle tissues. Current research suggests its activity might impact the efficiency of cellular energy utilization.
Biological function summary
C8orf30A contributes to the regulation of mitochondrial function and energy metabolism. It forms a part of a larger protein complex that participates in the cellular energy management. The presence of this protein influences the mitochondrial respiratory chain affecting the production of ATP—a critical energy currency of the cell. The modulation of energy dynamics by C8orf30A highlights its importance in maintaining cellular energy homeostasis.
Pathways
C8orf30A involvement reflects in the regulation of oxidative phosphorylation and glycolytic pathways. This protein interacts closely with enzymes and other proteins within these pathways to modulate energy production and balance. It associates with proteins like ATP synthase and complexes involved in electron transport reflecting an essential integrative role within metabolic pathways to harness energy efficiently.
Changes in C8orf30A levels connect to metabolic disorders including diabetes and metabolic syndrome. The protein's regulation influences factors related to these diseases impacting insulin sensitivity and energy utilization in cells. C8orf30A interacts with proteins such as glucose transporters and alters their function emphasizing its role in disease progression and providing potential targets for therapeutic intervention.