Abcam, ab192968, HRP Anti-APX2 antibody

Size: 100µL
Rabbit Polyclonal APX2 antibody - conjugated to HRP. Suitable for WB and reacts with Arabidopsis thaliana samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Arabidopsis thaliana APX2.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Conjugation:HRP,
Carrier free:No,
Reacts with:Arabidopsis thaliana,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Arabidopsis thaliana APX2.Q1PER6

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Purification notes->95%,Protein G purified, Storage buffer-pH: 7.4Preservative: 0.03% Proclin 300Constituents: PBS, 50% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
APX2 also known by its full name Ascorbate Peroxidase 2 plays a significant role in cellular mechanisms. This enzyme has a molecular mass of approximately 30 kDa and is predominantly found in chloroplasts in plant cells. APX2 catalyzes the conversion of hydrogen peroxide into water and oxygen using ascorbate as an electron donor. This action helps protect cells against oxidative damage by reducing reactive oxygen species levels.
Biological function summary
Enzymes like APX2 are vital components for maintaining cell health in plants. APX2 is a part of the antioxidant defense system which regulates reactive oxygen species and repairs damaged cellular components. It operates independently and does not appear to form part of a large protein complex. APX2 expression can change in response to environmental stressors such as high light intensity or drought showcasing its key role in plant stress responses.
Pathways
This protein plays an integral part in both the ascorbate-glutathione cycle and the oxidative stress response pathway which are important for detoxifying hydrogen peroxide in plants. Within these pathways it collaborates with enzymes like glutathione reductase and superoxide dismutase to coordinate the reduction of harmful oxygen species and support cellular resilience against stress.
The involvement of APX2 in managing oxidative stress may connect to several plant stress-related conditions such as leaf senescence and drought tolerance. The protein may interact with other stress-related proteins like catalase to mediate responses that prevent cellular damage in adverse conditions. Enhancing APX2 activity is considered a potential strategy in developing stress-resistant plants improving crop safety and yield under environmental pressure.