Abcam, ab20250, Anti-Testosterone 3 CMO antibody [3T16]

Size: 50µg
Mouse Monoclonal Testosterone 3 CMO antibody. Suitable for RIA and reacts with Chemical samples. Cited in 1 publication. Immunogen corresponding to Chemical / Small Molecule corresponding to Testosterone 3 CMO.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:3T16,
Isotype:IgG1,
Light chain type:unknown,
Carrier free:No,
Applications:RIASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.

Product details:
This antibody can be used for detecting and measuring testosterone levels in serum and tissue.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A/G, Storage buffer-Preservative: 0.02% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Testosterone 3 CMO also known as 3 CMO or 3 T-16 is a synthetic derivative designed for the study of testosterone-related mechanisms. This target acts as an immunogen stimulating immune responses against testosterone. It plays an essential role in creating specific antibodies that can recognize and bind to testosterone. Although the molecular weight of Testosterone 3 CMO varies depending on its conjugation to carrier proteins this derivative is typically produced in laboratories rather than expressed naturally in tissues.
Biological function summary
Testosterone 3 CMO serves as a valuable tool for researchers studying testosterone's role in the body. Testosterone a significant steroid hormone belongs to the androgen group and predominantly influences the development and maintenance of male characteristics. As it is not part of a natural protein complex Testosterone 3 CMO's primary purpose is to aid in generating testosterone-specific antibodies used in various diagnostic research applications that explore androgen functions.
Pathways
Testosterone 3 CMO plays a role in understanding how testosterone acts within critical physiological networks. One of these is the androgen receptor signaling pathway where it interacts with the androgen receptor (AR) impacting gene expression and cellular function. Another significant pathway involves the hypothalamic-pituitary-gonadal (HPG) axis a priority for regulating testosterone production. Testosterone association with proteins such as sex hormone-binding globulin (SHBG) is essential for transport and activity modulation within these pathways.
Researchers often utilize Testosterone 3 CMO for insights into conditions like androgenic alopecia and prostate cancer. Androgen disorders such as hair loss highlight testosterone interactions with enzymes like 5-alpha-reductase which converts testosterone to the potent dihydrotestosterone (DHT). In prostate cancer research Testosterone 3 CMO helps study how testosterone influences prostate cell growth. The interactions involve the androgen receptor critical for understanding cancer progression and devising treatment strategies.