Abcam, ab203827, Anti-SLC45A3 antibody [EPR18068]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal SLC45A3 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR18068,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
SLC45A3 also known as Prostate Cancer Associated Transcript 6 (PCAT6) is a member of the solute carrier family that functions primarily as a transporter. This protein has a mass of approximately 51 kDa. It is primarily expressed in the prostate but also found in other tissues though at lower levels. SLC45A3 is involved in transporting certain solutes which is important for maintaining cellular homeostasis.
Biological function summary
This transporter plays a critical role in regulating pH and solute concentration within the cells. SLC45A3 does not appear to belong to a large protein complex but it interacts with elements of the intracellular environment that modulate its activity. Its solute transportation role affects a range of cellular processes impacting overall cell health and function.
Pathways
SLC45A3 operates within the cellular homeostasis and metabolic pathways. It closely relates to the acid-base balance pathway ensuring that cells maintain optimal internal conditions. Additionally its function can link to the androgen receptor signaling pathway an important pathway in prostate tissue where it may interact indirectly with other transport proteins that assist in maintaining homeostatic balance.
SLC45A3 is significantly connected to prostate cancer and may also have implications in other types of cancer. It associates with the androgen receptor which plays a major role in the progression of prostate cancer. Understanding the dynamics of SLC45A3 can help in comprehending its role in these diseases potentially offering targets for new therapeutic strategies.