Abcam, ab204083, Anti-FAM98A antibody

Size: 100µL
Rabbit Polyclonal FAM98A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FAM98A aa 1-150.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human FAM98A aa 1-150. The exact immunogen used to generate this antibody is proprietary information.Q8NCA5

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
FAM98A also known as Family with Sequence Similarity 98 Member A is a cytoplasmic protein with a mass of approximately 26 kDa. This protein shows expression in various tissues including the brain and liver. It functions mechanically in processes involving RNA contributing to RNA-binding activities although the specific details of its RNA interactions remain to be fully understood.
Biological function summary
This protein acts within a larger multi-protein complex affecting cellular and molecular functions that are important for proper cell regulation. It participates in processes like gene expression modulation although the precise scope of its biological roles is still under investigation. FAM98A also appears to engage in interactions influencing cell cycle regulation which highlights its importance in maintaining cell stability.
Pathways
FAM98A integrates into significant cellular pathways such as TOR signaling and may also influence mitotic processes. It interacts with proteins like the RACK1 scaffolding protein suggesting a role in protein translation and signaling pathways. These interactions position FAM98A within important circuits that oversee cell growth and proliferation.
Changes in FAM98A function or expression could contribute to cancer and neurological disorders reflecting its involvement in cell cycle and regulatory processes. For instance in certain cancers its altered interaction with proteins like RACK1 may impact tumor progression. Meanwhile in neurological disorders disruptions in its RNA-binding role might link to dysregulation of neuronal functions. Further research could open additional insights into these associations.