Abcam, ab211542, Anti-CDKN2A/p16INK4a antibody [EPR20418]

Size: 20µL / 100µL / 1mL
Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) is a rabbit monoclonal antibody detecting CDKN2A/p16INK4a in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IP, ICC/IF . Suitable for Mouse . - Biophysical QC for unrivalled batch-batch consistency - Over 80 publications
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR20418,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse,
Applications:IP, Flow Cyt (Intra), ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:Expression levels of the CDKN2A/p16INK4a protein may vary with sample type. It's barely expressed in normal tissue, and mostly expressed in some tumour tissues, such as cervical cancer, breast cancer and so on. Moreover, only expressed in some cell lines. Please see images for recommended positive controls.Please navigate to the Product Protocol section for specificity details in Chinese.

Product details:
Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IP, WB in mouse samples.
Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) has been cited over 83 times in peer reviewed journals and is trusted by the scientific community.
Abcams high quality manufacturing and validation processes ensure Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) has 8 independent reviews from customers.
Anti-CDKN2A/p16INK4a antibody [EPR20418] (ab211542) specifically detects CDKN2A/p16INK4a (UniProt ID: P51480; Molecular weight: 18kDa) and is sold in a convenient trial size to enable initial testing (20 uL) and larger sizes for subsequent scaling up experiments (100 uL and 1 mL).
Conjugation-ready, carrier free format available for antibody clone EPR20418 -
ab23242
CDKN2A, also known as p16INK4a, is a crucial tumor suppressor gene involved in cell cycle regulation and cancer development. It encodes the p16INK4a protein, which inhibits cyclin-dependent kinases (CDKs) 4 and 6, preventing the phosphorylation of the retinoblastoma protein (Rb) and halting cell cycle progression from the G1 to the S phase.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle