Abcam, ab237811, Anti-ZNF695 antibody

Size: 100µL
Rabbit Polyclonal ZNF695 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Zinc finger protein 695.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Human Zinc finger protein 695.Q8IW36

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Purification notes-Purity greater than 95%., Storage buffer-pH: 7.4Preservative: 0.03% Proclin 300Constituents: PBS, 50% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ZNF695 also known as Zinc Finger Protein 695 has a mechanical role in DNA binding and transcriptional regulation. Its molecular weight is approximately 60 kDa. Scientists observe the expression of ZNF695 in various tissues with higher levels noted in certain tumor cells. Known for its zinc finger domains ZNF695 interacts directly with DNA segments influencing the transcription of specific genes within the genome.
Biological function summary
Zinc Finger Protein 695 influences gene expression without being part of a larger known protein complex. It plays a role in cellular processes like cell differentiation and proliferation. By modulating transcription ZNF695 impacts cellular responses to external signals contributing to the regulation of important physiological functions. Its activity can affect a range of cellular states reflecting the capability of transcription factors to mediate complex regulatory tasks within the cell.
Pathways
Zinc Finger Protein 695 interacts with transcriptional regulation and signal transduction pathways. It has connections with the Wnt signaling pathway which is important for cell growth and development and may influence other proteins like β-catenin within this pathway. Additionally ZNF695 might be linked to the PI3K/Akt pathway which is important for regulating the cell cycle and preventing apoptosis. These associations suggest potential roles in maintaining cellular homeostasis and responses.
Abnormal expression or mutations in ZNF695 associates with certain types of cancer particularly breast and prostate cancer. There may be an interaction with the protein p53 a well-known tumor suppressor involved in cancer biology. Dysregulation of transcription factors like ZNF695 could lead to altered gene expression profiles contributing to oncogenesis. Understanding these connections may present opportunities for developing therapeutic targets or biomarkers.