Abcam, ab238143, Anti-OPCML antibody [EPR22947-46]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal OPCML antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR22947-46,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
OPCML or Opioid-Binding Protein/Cell Adhesion Molecule-Like is a glycoprotein involved in cell adhesion processes. It weighs approximately 38 kDa and is located on the surface of cells within the nervous system and certain epithelial tissues. As a membrane-bound protein OPCML plays a role in modulating the interactions between cells and the extracellular matrix.
Biological function summary
OPCML influences cell signaling and adhesion through its interactions with other cellular proteins. It is not a part of a larger complex but its role in cell adhesion impacts the organization of cells and tissues. OPCML assists in maintaining proper cellular architecture and is essential for normal cellular communication.
Pathways
OPCML participates in pathways that regulate cellular adhesion and migration. It interacts with other proteins such as integrins and plays a role in the focal adhesion pathway. OPCML's involvement in these pathways helps to govern cell movement and positioning ensuring cells remain in their appropriate locations within tissues.
OPCML has connections to various types of cancers including ovarian and breast cancer. Changes in OPCML expression and function can disrupt normal cell adhesion contributing to cancer progression. OPCML's interaction with cadherins another group of adhesion proteins is notable in the context of these diseases as it can influence tumor spread and metastasis.