Abcam, ab239546, Recombinant Human HSPC152 protein (Tagged)

Size: 100µg
Recombinant Human HSPC152 protein (Tagged) is a Human Full Length protein, in the 1 to 125 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.
Key facts
Purity:>90% SDS-PAGE,
Expression system:Escherichia coli,
Tags:Tag free,
Applications:SDS-PAGE, Mass SpecSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Biologically active:No,
Accession:Q9UI30,
Animal free:No,
Carrier free:No,
Species:Human,
Storage buffer:pH: 7.2 - 7.4Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
HSPC152 also known as C19orf53 plays a role in various cellular processes. It has a molecular mass of approximately 14 kDa. Researchers have found this protein expressed in a wide range of human tissues with significant presence noted in organs such as the brain and liver. While specific subcellular localization can vary evidence suggests that HSPC152 predominantly resides in the cytoplasm.
Biological function summary
HSPC152 contributes to cellular homeostasis and regulation at multiple levels. While its standalone functions remain under investigation it is often involved as part of larger protein complexes. Studies have shown that it might interact with other proteins to influence cell cycle regulation implicating its potential role in maintaining cellular balance and responding to external stimuli.
Pathways
HSPC152 is associated with the regulatory processes in cell proliferation and apoptosis. It is speculated to interact within pathways such as the PI3K-Akt signaling pathway which is essential for cell survival. Connections between HSPC152 and proteins such as Akt and mTOR suggest it may contribute to modulating these pathways impacting varied cellular responses in different tissues.
Understanding the functions of HSPC152 extends to cancer and neurodegenerative conditions. Altered expression of HSPC152 has been observed in certain cancers hinting at its potential involvement in tumorigenesis. Furthermore its interaction with proteins like p53 known for roles in both cancer and neurodegenerative disease pathways suggests that further study may help in understanding the influence HSPC152 has in these contexts.