Abcam, ab2413, Anti-Fibronectin antibody

Size: 250µL
Anti-Fibronectin antibody (ab2413) is a rabbit polyclonal antibody detecting Fibronectin in Western Blot, IHC-P, ICC/IF . Suitable for Human, Mouse . - Over 970 publications - Trusted since 2002
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Light chain type:unknown,
Carrier free:No,
Reacts with:Mouse, Human,
Applications:ICC/IF, IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Native Full Length Protein corresponding to Human FN1.P02751

Product details:
Anti-Fibronectin antibody (ab2413) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human samples.
Anti-Fibronectin antibody (ab2413) has been cited over 977 times in peer reviewed journals and is trusted by the scientific community.
Abcam's high quality validation processes ensure Anti-Fibronectin antibody (ab2413) has high sensitivity and specificity.
Anti-Fibronectin antibody (ab2413) has 89 independent reviews from customers.
Anti-Fibronectin antibody (ab2413) specifically detects Fibronectin (UniProt ID: P02751; Molecular weight: 269kDa) and is sold in 250 µL selling sizes.
Fibronectin (FN1) is a glycoprotein that plays a critical role in the extracellular matrix (ECM) and is significantly upregulated in the tumor microenvironment. Fibronectin (FN1) facilitates tumor angiogenesis, providing essential nutrients to the growing tumor. It also aids in cancer cell invasion and metastasis through interactions with integrins and activation of signaling pathways like FAK/MAPK/ERK and Wnt. Additionally, fibronectin is involved in the epithelial-mesenchymal transition (EMT), which enhances the migratory and invasive capabilities of cancer cells.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.5Preservative: 0.05% Sodium azideConstituents: PBS, 0.096% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C