Abcam, ab245690, Anti-CD172 gamma antibody [OX117]

Size: 200µg
Rabbit Recombinant Monoclonal CD172 gamma antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SIRPG.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:OX117,
Isotype:IgG,
Light chain type:lambda,
Carrier free:No,
Reacts with:Human,
Applications:Flow CytSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Human SIRPG.Q9P1W8

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Preservative: 0.02% Proclin 300Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CD172 gamma also known as SIRP gamma or signal-regulatory protein gamma is part of the signal-regulatory protein family. This protein has a molecular mass of approximately 44 kDa. CD172 gamma is a transmembrane protein expressed mainly on the surface of immune cells including T lymphocytes and to a lesser extent on other specific blood cells. It acts through its extracellular Ig-like domains which enable it to participate in cell-cell interactions.
Biological function summary
CD172 gamma plays a role in immune response modulation. It functions as a part of a receptor complex that assists in cell signaling and communication. This involvement includes facilitating interactions between immune cells and presenting antigens which can impact cell activation and response. CD172 gamma has specific interactions that contribute to the regulation of the immune system further enhancing its role in defining cellular activity.
Pathways
CD172 gamma engages in immune signaling pathways. This protein is notably associated with the antigen presentation pathway where it plays a significant role in adaptive immune response. It works in conjunction with other proteins like SIRP alpha and SIRP beta forming a network that modulates immune cell signaling and activity. It influences the pathway interactions that determine how immune cells respond to various stimuli.
CD172 gamma has connections to immune-related conditions. In particular this protein has been studied in the context of autoimmune diseases where its role in immune signaling can affect disease progression. It is also linked to certain hematological disorders influencing the behavior of blood cells. CD172 gamma interacts with proteins like CD47 in these disease processes playing a distinct role in the modulation and potential progression of these conditions.