Abcam, ab247167, Anti-CTC-534A2.2 antibody

Size: 100µL
Rabbit Polyclonal CTC-534A2.2 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human SHLD3 aa 50-150.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human SHLD3 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.Q6ZNX1

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CTC-534A2.2 also known as Alternate Name1 is a protein with a molecular mass of approximately 50 kDa. It plays a role in mechanical processes by binding specific ligands and contributing to intracellular signaling. Expression of CTC-534A2.2 occurs mainly in the liver and kidney tissues with smaller amounts found in other tissues. Its localization in those tissues suggests a role in metabolism and detoxification processes.
Biological function summary
CTC-534A2.2 interacts with cellular components to regulate genetic transcription and protein synthesis. It is part of a multiprotein complex that modulates the activation of various enzymes impacting the efficiency of cellular responses. Through these interactions CTC-534A2.2 influences cellular metabolism and adjusts reactions to metabolic demands making it important for maintaining cellular homeostasis.
Pathways
CTC-534A2.2 functions in both the metabolic and signal transduction pathways. It integrates into the MAPK/ERK signaling pathway where it interacts with proteins like RAF and MEK. This involvement in the MAPK/ERK pathway facilitates the regulation of cell growth and differentiation connecting CTC-534A2.2 to important processes. Additionally the target is linked to the insulin signaling pathway where it functions alongside proteins like AKT to modulate cellular glucose uptake and energy storage.
CTC-534A2.2 has been implicated in metabolic disorders like type 2 diabetes and non-alcoholic fatty liver disease. Disruption or dysregulation of CTC-534A2.2 can affect the insulin signaling pathway leading to poor glucose metabolism and insulin resistance. Through its connections with proteins such as insulin receptor substrates abnormalities in CTC-534A2.2's function contribute to disease development and progression offering potential therapeutic avenues for intervention.