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BRAND / VENDOR: Abcam

Abcam, ab248784, Anti-RPL26L1 antibody [EPR8478] - BSA and Azide free

CATALOG NUMBER: ab248784
Regular price$0.99
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Product Description

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal RPL26L1 antibody. Carrier free. Suitable for IHC-P, ICC/IF, WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR8478,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:ICC/IF, IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab248784 is the carrier-free version of
ab137046
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
RPL26L1 also known as ribosomal protein L26-like 1 is a protein that functions in the translation process within cells. This protein has a mass of approximately 17.4 kDa and is part of the ribosomal machinery specifically associated with the 60S ribosomal subunit. Expression of RPL26L1 is found in tissues with high protein synthesis demand including the liver and testis indicating its role in protein production.
Biological function summary
RPL26L1 acts as a component of the ribosome contributing to protein biosynthesis by facilitating the assembly of ribosomes and ensuring the synchronized translation of mRNA into polypeptides. RPL26L1 participates in forming a ribonucleoprotein complex essential for maintaining the structural stability of ribosomes during translation. This function is critical for efficient cell growth and protein expression.
Pathways
Ribosome-associated activities see RPL26L1 play a significant part in the mRNA translation pathway. Involvement in the translation initiation process links RPL26L1 closely with other ribosomal proteins such as RPL26 which is involved in regulating mRNA translation initiation and elongation. Together these proteins ensure the fidelity and efficiency of protein synthesis connecting RPL26L1 to the foundational processes of gene expression.
Disruptions in RPL26L1 function can relate to conditions such as Diamond-Blackfan anemia a rare genetic disorder linked to faulty ribosomal proteins. In this context RPL26L1 interaction with proteins like RPS19 reflects its role in the pathology of diseases that originate from ribosomal protein malfunctions. Maintaining appropriate RPL26L1 function is essential for ribosomal integrity and overall cellular health.


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Collaboration

Tony Tang

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