Abcam, ab249981, Anti-C16orf88 antibody [EPR12561] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal C16orf88 antibody. Carrier free. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR12561,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab249981 is the carrier-free version of
ab177476
Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please
contact us
for more information.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C16orf88 also known as Chromosome 16 Open Reading Frame 88 is an uncharacterized protein that plays a role at the cellular level. With a molecular mass of approximately 44 kDa C16orf88 is expressed in various tissues with substantial expression in the brain and testis. Its exact functions are not fully understood but research suggests it may participate in cellular structural frameworks or signaling pathways due to its presence across different cell types.
Biological function summary
The protein influences cellular processes by contributing to the regulation of cell cycle or structural integrity. Current studies indicate that C16orf88 might form part of a multiprotein complex which supports its role in maintaining cellular organization or facilitating communication between signaling molecules. Although information remains limited C16orf88's expression pattern suggests it may affect cellular differentiation and developmental biology particularly in neural tissues.
Pathways
Existing evidence connects C16orf88 to neurological and reproductive pathways. It may join key components of MAPK/ERK signaling pathways and demonstrate interactions with proteins such as ERK1/2 which are known regulators of cell division and differentiation. Participation in these pathways positions C16orf88 as a contributor to signal transduction that affects overall physiological responses and developmental processes.
C16orf88 shows potential linkage with neurodegenerative diseases and reproductive health issues. Disruption in its function or expression has associations with conditions like Alzheimer's disease where proteins such as TAU related to C16orf88 play a central role in disease progression. Similarly abnormal activity can trigger reproductive disorders by affecting related proteins involved in testicular function though precise mechanisms and pathways require further research for clarity.