Abcam, ab264474, Anti-OPCML antibody [EPR22947-46] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal OPCML antibody. Carrier free. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR22947-46,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Rat, Human,
Applications:WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab264474 is the carrier-free version of
ab238143
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
OPCML or Opioid-Binding Protein/Cell Adhesion Molecule-Like is a glycoprotein involved in cell adhesion processes. It weighs approximately 38 kDa and is located on the surface of cells within the nervous system and certain epithelial tissues. As a membrane-bound protein OPCML plays a role in modulating the interactions between cells and the extracellular matrix.
Biological function summary
OPCML influences cell signaling and adhesion through its interactions with other cellular proteins. It is not a part of a larger complex but its role in cell adhesion impacts the organization of cells and tissues. OPCML assists in maintaining proper cellular architecture and is essential for normal cellular communication.
Pathways
OPCML participates in pathways that regulate cellular adhesion and migration. It interacts with other proteins such as integrins and plays a role in the focal adhesion pathway. OPCML's involvement in these pathways helps to govern cell movement and positioning ensuring cells remain in their appropriate locations within tissues.
OPCML has connections to various types of cancers including ovarian and breast cancer. Changes in OPCML expression and function can disrupt normal cell adhesion contributing to cancer progression. OPCML's interaction with cadherins another group of adhesion proteins is notable in the context of these diseases as it can influence tumor spread and metastasis.