Abcam, ab267414, Anti-Gram Positive Bacteria LTA antibody [G43J]

Size: 100µg
Mouse Monoclonal Gram Positive Bacteria antibody. Suitable for WB and reacts with Bacillus subtilis, Gram Positive Bacteria samples. Cited in 5 publications.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:G43J,
Isotype:IgG1,
Carrier free:No,
Reacts with:Bacillus subtilis, Gram Positive Bacteria,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Specificity:THis antibody reacts with Gram positive bacteria Lipoteichoic acid (LTA) in bacterial and infected tissue samples.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2Preservative: 0.1% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The term 'Gram-positive bacteria' refers to a group of bacteria that retain the crystal violet stain during the Gram stain procedure. This staining technique distinguishes them from Gram-negative bacteria by their thicker peptidoglycan layer. Common examples of Gram-positive bacteria include Bacillus subtilis which is often used as a model organism in research. Gram-positive bacteria are characterized by a thicker cell wall that contains teichoic acids contributing to a density that assists in stain retention. This structural distinction enables them to be easily identified under a microscope during laboratory diagnostics and microbial analyses.
Biological function summary
Gram-positive bacteria exhibit diverse functions and roles within ecosystems and human health. They play significant roles in symbiotic relationships and nutrient cycling as well as act as pathogens in various infections. They can form biofilms and can sporulate enhancing their survival in harsh environments. Gram-positive bacteria are not part of a specific complex but they engage in diverse interactions with other microorganisms and host tissues impacting biological processes such as colonization and infection.
Pathways
Gram-positive bacteria participate in numerous important biological and metabolic pathways. For instance they are involved in the glycolytic pathway and the peptidoglycan synthesis pathway important for maintaining their cell structure and energy metabolism. Proteins like penicillin-binding proteins play an important role in the synthesis and modification of peptidoglycan. Similarly autolysins are involved in cell wall remodeling and turnover which are important for cell growth and division.
Gram-positive bacteria are connected to several infections including skin infections and pneumonia. Staphylococcus aureus a well-known Gram-positive bacterium can lead to conditions ranging from minor skin infections to severe diseases like sepsis. These bacteria interact with host immune proteins such as cytokines often resulting in inflammatory responses. Additionally Streptococcus pneumoniae another Gram-positive bacterium is associated with pneumonia and meningitis illustrating their relevance in public health concerns.