Abcam, ab283818, Anti-IL-1 beta antibody [RM1009]

Size: 20µL / 100µL / 1mL
Anti-IL-1 beta antibody [RM1009] (ab283818) is a rabbit recombinant multiclonal antibody detecting IL-1 beta in Western Blot, Flow Cytometry, IP, IHC-P . Suitable for Human, Mouse, Rat . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 30 publications
Key facts
Host species:Rabbit,
Clonality:Multiclonal,
Clone number:RM1009,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:IHC-P, ICC, Flow Cyt, IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:IL-1 beta is not present under homeostatic conditions, and it is induced and secreted only upon inflammatory signals. Stimulation may be required for the detection of IL-1β, no matter in precursor or mature form (PMID: 22019906). IL-1β is a secreted protein, it is recommended to treat cells with anti-secretion reagents (e.g. Brefeldin A) when test IL-1β using whole cell lysate in WB.Please navigate to the Product Protocol section for specificity details in Chinese.

Product details:
Product Specifications
Anti-IL-1 beta antibody [RM1009] (ab283818) is a recombinant rabbit multiclonal antibody which is comprised of multiple monoclonal antibodies targeting different epitopes and recapitulating the performance of a polyclonal. Each component clone was developed by Abcam using patented rabbit monoclonal antibody technology.
Anti-IL-1 beta antibody [RM1009] (ab283818) is validated for use in Flow Cyt, ICC, IHC-P, IP and WB in human, mouse and rat samples.
Anti-IL-1 beta antibody [RM1009] (ab283818) specifically detects IL-1 beta/ Interleukin-1 beta (UniProt ID: P01584; Molecular weight: 31kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL).
Quality and Validation
Abcams high quality manufacturing and validation processes ensure anti-IL-1 beta antibody [RM1009] (ab283818) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
The specificity of anti-IL-1 beta antibody [RM1009] (ab283818) has been confirmed by testing in knockout samples.
Related Products
Conjugation-ready, carrier free format available for antibody clone RM1009 -
ab283822
What are recombinant multiclonals?
Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including:
- The sensitivity of polyclonal antibodies by recognising multiple epitopes
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
View our range of
recombinant multiclonal antibodies
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents

Properties and Storage Information:
Form-Liquid, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle