Abcam, ab286964, PF-9366

Size: 5mg
MW 350.8 Da, Purity >98%. An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform (IC 50 = 420 nM). PF-9366 inhibits cellular S-Adenosyl-L-methionine (SAM) production with an IC 50 of 1.2 μM in H520 lung carcinoma cells.
Key facts
CAS number:72882-78-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:350.8 Da,
Molecular formula:C20H19ClN4,
PubChem:12612431,
Nature:Synthetic,
Solubility:Soluble in DMSO,
Biochemical name:PF 9366-Bio-X,
Biological description:An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform (IC50 = 420 nM). PF-9366 inhibits cellular S-Adenosyl-L-methionine (SAM) production with an IC50 of 1.2 μM in H520 lung carcinoma cells.,
Canonical smiles:CN(C)CCC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=C2)C4=CC=CC=C4,
InChi:InChI=1S/C20H19ClN4/c1-24(2)11-10-19-22-23-20-13-16(14-6-4-3-5-7-14)17-12-15(21)8-9-18(17)25(19)20/h3-9,12-13H,10-11H2,1-2H3,
InChiKey:LYLASWLQCMKZAT-UHFFFAOYSA-N,
IUPAC Name:2-(7-chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethanamine

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2244 PF-9366. B2244-5 is the same size as the 5 mg size of ab286964.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes