Abcam, ab287002, Liproxstatin-1

Size: 5mg / 25mg
MW 340.8 Da, Purity >98%. A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice. Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice.
Key facts
CAS number:950455-15-9,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:340.8 Da,
Molecular formula:C19H21ClN4,
PubChem:135735917,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25mM,
Biochemical name:Liproxstatin-1,
Biological description:A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice.Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice.,
Canonical smiles:C1CNCCC12C(=NCC3=CC(=CC=C3)Cl)NC4=CC=CC=C4N2,
InChi:InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23),
InChiKey:YAFQFNOUYXZVPZ-UHFFFAOYSA-N,
IUPAC Name:N-[(3-chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-imine

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2312 Liproxstatin-1. B2312-5 is the same size as the 5 mg size of ab287002.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes