Abcam, ab287043, CC-90003

Size: 5mg
MW 458.4 Da, Purity >98%. CC-90003 is a potent extracellular signal-regulated kinases (ERK1/2) inhibitor. CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
Key facts
CAS number:1621999-82-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:458.4 Da,
Molecular formula:C22H21F3N6O2,
PubChem:90331177,
Nature:Synthetic,
Solubility:Soluble in DMSO to >100 mM,
Biochemical name:CID 90331177,
Biological description:CC-90003 is a potent extracellular signal-regulated kinases (ERK1/2) inhibitor. CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.,
Canonical smiles:CC1=CC(=C(C=C1)NC2=NC(=NC=C2C(F)(F)F)NC3=CC(=NC=C3C)OC)NC(=O)C=C,
InChi:InChI=1S/C22H21F3N6O2/c1-5-18(32)28-17-8-12(2)6-7-15(17)29-20-14(22(23,24)25)11-27-21(31-20)30-16-9-19(33-4)26-10-13(16)3/h5-11H,1H2,2-4H3,(H,28,32)(H2,26,27,29,30,31),
InChiKey:ILUKRINUNLAVMH-UHFFFAOYSA-N,
IUPAC Name:N-[2-[[2-[(2-methoxy-5-methylpyridin-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2419 CC-90003. B2419-5 is the same size as the 5 mg size of ab287043.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C